Shrimp Treadmills and 5 Other Odd Research Projects

Scientists study a lot of complicated things and when they’re designing experiments They usually need to do some creative problem-solving sometimes that can mean turning to decades-old research in a completely different field for help applying an odd method or Using clever stand-ins for rare or expensive materials and without context this kind of scientific research might come across as weird useless or a waste of money But if you take a closer look you’ll usually find that seemingly silly science can have a huge sometimes even life-saving effect on society so here are six times that important scientific advancements have come from Out-of-the-box thinking about a decade ago a clip of a shrimp running on a treadmill went viral and since then it’s been spread around on And offline as a poster child for wasteful spending now there was a National Science Foundation grant of over four hundred and twenty five Thousand dollars that was awarded in 2002 to the team that made that video clip, but everyone crying What a waste is taking that number and the clip Completely out of context the researchers weren’t just plopping Shrimp onto tiny treadmills to see how fast they could run this was part of a much larger study of how climate related Changes in the ocean affect the health of commercial seafood species how these critters Respond to stress affects their survival and ocean ecosystems which is pretty important by itself But at the very least you’d probably care whether the shrimp going into your belly was able to fight off Bacterial infections before it became food for these experiments the researchers made their first Treadmill entirely from scraps lying around the lab for less than 50 bucks Shrimp are active creatures so letting them Why around isn’t a good model for how their bodies would respond and fight off an infection? In the real world so they used this equipment to compare the health and behavior of sick and healthy shrimp in Tanks that simulate stressful ocean conditions that are caused by climate change Like low oxygen or high acidity that original grant led to four years of research and 7 published papers on multiple species of crustaceans Not just the Pacific why shrimp from that video the scientists found that being sick seems to lower their activity and bad water Conditions make it harder for them to move and fight off infection and since then the lead Researchers have also been looking into how the side effects of climate change affect How crustaceans express certain genes that influence their health speaking of climate science there are? Traditional ways to study what Earth’s climate was like thousands of years ago and then there’s crystallized pee the hyrax is a cave dwelling mammal a bit bigger than a guinea pig found in the dry climates of Sub-saharan Africa in the Middle East colonies of 50 or so creatures all used the exact same communal toilet called a midden over many generations One mitten in South Africa has been building up for the past fifty five Thousand years these mittens can be found in caves or under rock ledges and grow to be several meters across Inside them layers of goopy urine crystallize into an amber like substance called high ricean Which by the way is used in some perfumes? Dry regions lack the usual evidence used to study what the earth used to look like like layers of sediment that form in lake beds or peat bogs But scientists can cut through a huge mitten to see the individual layers And analyze the urine poop and dust blend like how a climatologist uses ice cores Or cross-sections of trees specifically by looking at the ratios of different elements like carbon and nitrogen They can see how much vegetation was available to eat And how dry it was? From hundreds to tens of thousands of years ago for example some climate models suggest that because of slight shifts And how the earth was orbiting the Sun about six thousand years ago the northern hemisphere got drier while the southern got humid but some Researchers found that hyrax mittens tell a different story the southern hemisphere may have become drier to unboiled Like a cool science demo in a take that entropy kind of way But it turns out the trick has some pretty important application when you heat a raw egg some of the bonds in the egg white proteins break So they change shape and get all knotted up together unboiled Means from each other which gives them space to Reform bonds and fold back into their original shape on their own and a team of researchers Found a way to do that more simply the ever before in 2015 first They took a small piece of hard-boiled egg white and dissolved it in a solution of urea the same compound found in urine so Yeah It becomes inedible really fast that breaks up the mass of tangled proteins into microscopic lumps making them easier to manage then they put that solution inside a vortex fluid device or VFD this spins it super fast at 5000 times a minute So a thin film flows up against the glass tube wall the closer the fluid is to the wall the faster its spinning the difference In speed creates a force that makes the proteins untangle from each other and once they’re separated they can naturally Refold the researchers used chicken eggs in this experiment mostly because they’re cheap but it also let them test a couple of different proteins including a Structural one called caviola ‘none it takes four days for a conventional method to untangle it but it took the VFD only minutes improperly folded or tangled proteins are expensive waste in lots of industries especially medical research and pharmaceuticals so this technique means that non-functional proteins can be Refolded and hopefully reused for example some antibody is used in cancer treatments are developed inside Expensive hamster ovary cells, but with VFDs. They could be grown in something cheaper That’s more likely to lead to folding errors because the proteins can be fixed this would lower the cost to make them which could be Passed on to people who need these treatments to help save more lives speaking of saving lives another study That sounds silly But had a huge impact involved giving baby rats back rubs back in 1979 Researchers were trying to learn what? Factors could affect compounds involved in baby rat growth to avoid dealing with protective mama rats the researchers separated them But to their surprise the compounds that they were trying to study stopped Increasing as the separated pups got older experiments ruled out other factors like Nutrition and they found that a mother’s grooming and licking was important for healthy growth the researchers then tried taking a tiny brush like the one you would use to clean a camera lens and rubbed the pups back and the baby rats made normal amounts of those growth compounds again a psychologist working in Pediatrics later learned of the study and applied it to her work with human infants born prematurely and her study Demonstrated that 15 minutes of gentle massage three times a day caused preemie babies to gay wait 47% faster than those left alone in incubators, which was standard practice Even though they were eating the same amount the massaged babies nervous systems also matured faster So they became more active and alert and on average the babies also spent six fewer days in the hospital Infant massage therapy is now used in hospitals across the u.s. and has saved an Estimated four point seven billion dollars a year in health care costs all these researchers were awarded a Golden Goose award in 2014 for u.s. federally funded research that seems unusual But has a major impact on society in 2016 a Golden Goose award was given to researchers who took a study about honeybees and applied it to of all things The internet the research began in the 1980s with studies modeling how honeybee colony is hunt for nectar This is harder than it might sound because patches of flowers are different distances away Bloom at different times and have different amounts of nectar so their value to a bee changes over time because these scientists monitored how each Individual bee forged in a colony. They had to glue tiny numbers on to over 4,000 of them by hand and they were able to generate a computer model of the bees Decision-making strategies in 2002 the model they created was adapted for something that might seem totally different Internet traffic management instead of nectar Companies that owed web hosting servers are like bees who want to collect the most amount of money from the websites and apps the request To use them, so you can find them online servers can use the honeybee algorithm it helps them modify How they distribute their time depending on changing supply and demand like when a bunch of people all decide to visit a Science Museum’s website To buy a purple dinosaur hoodie featured on a hit Netflix show that site needs more server capacity basically the honeybee Algorithm works like an advertisement board that tells a company’s servers about the current needs for a bunch of different websites That’s for high demand and high paying Websites pop up more often and stay up longer to make sure more servers are dedicated to them, but the honeybee algorithm also helps us by making the internet run more smoothly to save time and hopefully keep suddenly popular pages from crashing and speaking of Optimization you might not think a brainless single-celled organism could grow up to become a city planner But let me introduce you to Fez Aaron Polly cephalo researchers revealed in 20:10 that it can grow into a structure that mimics the layout of real-world Transport systems they placed this slime mold on a 2d map of the Tokyo area With oat flakes for 36 nearby cities the slime mold started at Tokyo and sent out branches Uniformly as it searched for food and as soon as I found the tasty flakes the cell chunks between cities grew larger and the unnecessary Branches shrunk away that way it can sustain Itself while keeping its body plan really efficient to save energy over the course of 26 hours it had formed a network of thin tubes That looked a lot like Japan’s rail network similar results happened across multiple tests based on resources the slime molds network was a little more efficient than Japan But the real transport system had better resilience meaning it could bounce back if any of the city connections failed most important Takeaway from this research is that the slime mold Generated a really efficient network in way less time than we would using a method that engineers couldn’t do in real life It’d be like putting railways everywhere, and then destroying the ones that didn’t perform Well other researchers have run similar Experiments simulating different countries one group found that of the 14 countries or regions they tested Malaysia Italy and Canada’s major Transport networks matched the slime mold the best the USA on the other hand was one of the worst however not all that research Considers natural barriers like mountains or bodies of water computer models derived from these studies could be used when we designed more transport for people or resources Especially to help balance the cost of construction with the benefit of reaching lots of places that would put the slime molds out of work of course but maybe they’d still Consult on especially tricky layouts studies like these show that you can’t judge the value of a scientific experiment by how unusual The methods seem something might seem funny at first glance But maybe researchers are finding really clever solutions to complex problems Thanks for watching this episode of scishow if you’d like to keep learning about all kinds of weird science with us You can go to and subscribe

100 thoughts on “Shrimp Treadmills and 5 Other Odd Research Projects”

  1. I wonder how many people saw that Shrimp, and thought “Wasteful govern,ent spending, Thanks Obama”
    And don’t have the patience to listen to a sentence or two to explain why this is useful.

  2. Could the travelling salesman problem be solved by pouring water into pipes that represent the routes? The water that reaches the farthest first could be a good indicator of a short route

  3. you guys should animate your programs and just narrate behind the camera, you show to much of youre faces and the human appearance distract the main focus of learning…

  4. So… the shrimp on the treadmill, as you describe it, is, in fact, a waste of money. It was an experiment that private industry could spend private dollars on to test to see how their product is good to sell. How, again, is that a good investment in taxpayer dollars? And oddly enough, the result (being sink makes them less active, etc) could have been told to you by a random guy on the street for a single ten dollar bill.

    I don't think you get the concept of "taxpayers money vs private industry money" when people are talking about government wasting money. Did the shrimp industry pay the government back for the research or was it a handout to them? Doe the phrase "obvious result is obvious' mean anything today?

  5. So… the Honeybees are anti-Net Neutrality. They want different server space and time as needed rather than equal for every bee.

  6. Lmao, the reason we cook shrimp is to kill those 'bacterial infections' and parasites, if cooking shrimp didn't do either of those things, we wouldn't cook them now would we, who gives a s**t about things we can not possibly hope to control without expending an ungodly amount of money.

  7. Back when I was in college a bunch of us hung out in a certain proffessor's lab. One of the things we did while hanging out in our smoking area (He smoked and had tenure, thus his lab was the smoking area for those of us that were on his good side. The Dean was also a smoker and HE would hang out in there…) Anyway, one of our favorite "games" was an ongoing contest to see who could come up with the oddest research that actually got funded/published … There were some "dozies" (and there are the Iggy's, backed and awarded annually at Harvard by "real" Noble Laureates…) but in the mumble years since I left the university, those off the wall studies and their results have been of more "use" in my real world "career" (Sr Scientist, Directer of R&D) than 99% of the stuff that was put out in my classes…

  8. if you arent a fan of how olivia looks you can go ahead and open a new tab and Google search something else to look at, maybe something more your speed, something like a small mound of dirt, or a pistachio shell, maybe both combined

  9. Science lady: "VFD"
    Me: pulls out volumes of Lemony Snicket's A Series of Unfortunate Events and confirms existence of the Illuminati

  10. Yea my own experiment made me realize this. Some how well I know how but to keep the comment shorter lets go with somehow. Ok somehow I got it in my head that marine aquarium salt could help plants grow. Sounds ridiculous right? I thought it was going to be a wast of time as well but two years in and my plants are telling a different story. Let's just say am all in now and my experiment continues.

  11. 9:40 It's a mistake to say engineers can't build a network this way in real life. They can, and do. In computer simulations. The slime mold is performing a process that is very easy to replicate in silico. Also, computer models can do this a lot faster than a slime mold.

  12. Can you do a video on the ingredients in vaccines? Explain in depth how aluminum and formaldehyde are healthy and necessary.

  13. I think the "shrimp on a treadmill" became an icon related to spending for it's own imagery. It really brings to mind the condition most people are in when in debt, or even the position game companies put you in with their "continued monetization strategies", I don't think it was ever about the experiment ITSELF being a waste.

  14. I haven't watched scishow in months(not that I stopped enjoying it, I just go through weird phases where I stop watching a channel for no reason) but it's sad that Olivia gets hate.

  15. … and this is why the general population shouldn't diminish the activities of those more intelligent than them e.g. scientists.

  16. the baby rat thing is great because the rats probably weren't brutally murdered in experiments and got back rubs and helped babies thats the only kind of animal experimentation thats kind of okay

  17. "If the solutions were always obvious we wouldn't need to do experiments in the first place."

    It's the experiments we do in ways and on things we wouldn't normally think to do, that often lead us to the discoveries we didn't know existed or in turn that we even needed. . . Because they are unusual yet done well.

  18. Maybe we should stop eating what God created to clean the waters. Do you think if the oceans which produce most of our oxygen were CLEAN that the CLIMATE might be better?
    Let's think! The oceans give us most of our oxygen. Now that the garbage eaters are being fished by the 100,000s pounds, what is eating the decay in the oceans? Guess what that decay releases into the water and then into the air! CARBON DIOXIDE.

    See… I just answered the entire question for FREE.

    And you need a STUDY to tell you to TOUCH BABIES? Yes. Worthless research. If someone needs to be TOLD to HOLD A BABY, they should be sterilized immediately and removed from their "science jobs".

  19. So instead of letting a bunch of politicians blow billions on pushing a transport system that turns out to be crappy, we should let slime molds do the job. Sounds perfect to me. Actually, I would trust a slime mold more than some politicians in many cases, now that I think about it.

  20. Never doubt science. Science is life.

    No really, though, these were some important studies. It is possible for science to be wrong but in these cherry picked examples they are likely not. Good job.

    I'm not trying to insult -_- just joking.

  21. If they can untangle proteins that means that they're one step closer to curing prion diseases! This is so exciting!

  22. I'm building our first family piss crystal. may my great great great grandkids have a large and dense communal piss crystal.

  23. thanks for Clearing up the wrong notions people got from the Shrimp treadmill study. i hate it when people who dont even understand what its about say "meeeh thats Money wasting"
    and the rest of the Video was very interesting. well done!

  24. i am so angry at how many sexist pigs in the comments keep criticizing host Olivia!!! this is a scishow video, i expect better, smh. @ host Olivia: you're doing amazing spreading the gospel of science, and you are looking fantastic while doing it!!

  25. Also — and this is just me — but the editing makes Blossom sound like someone reading a run-on sentence out loud.

  26. Imagine giving your little pet baby mouse a small brushie brushie and then accidentally saving thousands of babies plus saving the United States 4.7 billion dollars a year

  27. People use the same argument for space exploration, but have no idea how much the research from it has changed and impacted he world.

  28. My bio 12 teacher showed us the slime mold forming Canada's Pacific Railway cause he didn't want to end the class early and have bunch of bored grade 12's walking around in the hallway. #notsofondhighschoolmemories

  29. We should make meditation a sport! You are only allowed to meditate to complete, you may also lose or win mediating (even though you can only win) you're welcome word

  30. Regarding #3: you mention VFD. Is that the same group from the Netflix series, "Lemony Snicket's A Series of Unfortunate Events"? That would be odd… XD

  31. Good science stories. So I'll overlook the silver booger. (That thing hanging from your nose. Sometimes It's better to be cruel to be kind. Most of us are people soooo…. ya know … the emperor's new clothes etc. etc. Don't be fashion easy.)

  32. If this happens to the shrimp when water is messed with, no wonder humans are so screwed up, with all that has been done to our own water supply!

  33. I was once told that my university spent too much on research, as evidenced by the fact that we were researching animals with silly names, like the Tsetse fly.

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